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Abiquin Hydroquinone, Tretinoin & Fluocinolone Cream 15g
Abiquin Cream (Hydroquinone Tretinoin And Fluocinolone) is prescribed for the short-term treatment of moderate to severe facial melasma. Patients should avoid sun exposure while using this cream and apply a broad-spectrum sunscreen with at least SPF 30.
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✅ Description:
Abiquin Cream combines three active agents—Fluocinolone Acetonide, Hydroquinone, and Tretinoin—which are commonly used in the management of melasma.
- Fluocinolone Acetonide is a topical corticosteroid that helps reduce inflammation.
- Hydroquinone is a skin-lightening agent that interferes with melanin production by inhibiting the tyrosine-tyrosinase pathway.
- Tretinoin is a keratolytic that promotes skin cell turnover.
Though the exact mechanism by which the combination works against melasma is not fully understood, the synergistic action of these components provides a therapeutic benefit.
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✔️ Dosage & Administration
- Apply once daily at night, at least 30 minutes before bedtime.
- Cleanse the face and neck with a gentle cleanser, rinse, and pat dry.
- Apply a thin layer to the melasma-affected areas, extending about half an inch onto the surrounding normal skin. Gently massage the cream into the skin.
- During daytime, apply sunscreen and wear protective clothing. Limit sun exposure.
- Moisturizers and makeup may be used during the day.
Pediatric Use: Safety and efficacy in children have not been established.
✔️ Side Effects
Some users may experience:
- Mild to moderate redness, dryness, peeling, burning, or itching at the site of application
- Rarely, severe allergic reactions such as difficulty breathing or asthma exacerbation
✔️ Avoid using:
- Abrasive or medicated soaps
- Products with alcohol or strong astringents
- Drying cosmetics
- Keratolytic products or other irritants
- Other topical or systemic agents that cause photosensitivity
✔️ Contraindications
Do not use in patients with known hypersensitivity to Fluocinolone Acetonide, Hydroquinone, Tretinoin, or any ingredient in the formulation.
✔️ Pregnancy & Lactation
Pregnancy:
- Category C. Contains tretinoin, which has been linked to fetal harm in animal studies.
- Should only be used in pregnancy if the expected benefits outweigh potential risks.
Lactation:
- While it’s unclear if topical use leads to significant drug levels in breast milk, systemic corticosteroids can appear in breast milk.
- Caution is advised when used by breastfeeding mothers.
✔️ Precautions & Warnings
- Irritation from Hydroquinone and Tretinoin may occur; this includes redness, itching, dryness, and mild burning.
- If severe irritation or allergic reaction occurs, discontinue use.
- Contains Fluocinolone Acetonide, which can be absorbed through the skin and may lead to reversible suppression of the HPA axis, potentially causing Cushing's syndrome, high blood sugar, or glucosuria.
- Discontinue use if systemic effects are observed; normal HPA axis function typically returns after stopping the cream.
✔️ Storage:
Store in a cool, dry place away from light. Do not freeze. Keep out of children’s reach.
Disclaimer:
ePharma sole intention is to ensure that its consumers get proper
information as musch as possible. Although we do not guarantee the
accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.
